Ion Mobility Fundamentals & Applications
Ion Mobility coupled with Mass Spectrometry (IM-MS) is a very powerful and versatile technique. Although first described by McDaniel et al in 1962, only relatively recently (the last 10 years or so) it has gained wide popularity, primarily due to the commercialisation of the technology. The 2019 SGMS School is designed to give a broad overview of the various flavours of IM-MS and a detailed description on how major MS vendors have implemented the IM technology, accompanied with examples of practical applications.
The 37th meeting of the SGMS will take place at the Dorint Resort Blüemlisalp Beatenberg, 24-25 October 2019 high above Lake Thun in the Bernese Oberland, with a scenic view of the Swiss Alps!
The meeting will be preceeded by the 2nd SGMS School on Ion Mobility: Fundamentals and Applications
Confirmed Speakers for 2019
- Vicki Wysocki (The Ohio State University) - [ abstract ]
- Dietrich Volmer (Humboldt University Berlin) - [ abstract ]
- Andrea Büttner (Friedrich-Alexander-Universität Erlangen-Nürnberg) - [ abstract ]
- Valérie Gabelica (University of Bordeaux, France) - [ bio ]
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|Single Room Occupancy
|Double Room Occupancy
|Student (double room - indicate roommate)
|Accompanying person (indicate roommate)
A surcharge of CHF 50 will be enforced to all payments submitted after the meeting.
- Early abstract registration: July 15th (Poster/Oral acceptance will be notified by September 1st).
- Abstract registration: September 1st (Poster/Oral acceptance will be notified by September 21st).
- Standard registration: August 31st (Includes one night at the Dorint hotel, Thursday Apéro and SGMS dinner, Friday breakfast, coffee breaks).
- Late registration: October 1st
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Short Oral Contributions: Early deadline for abstract submission for both talks and posters is July 15th. The extended deadline is September 1st. Abstracts submitted before July 1st will have priority. Please submit your abstract including author's name and address directly to registration(at)sgms(dot)ch The abstract should not exceed 2500 characters.
Guidelines for the submission of abstracts:
- Save your file as LASTNAME_TITLE.xxx
- Include the name of the contact person (spell out first name) as well as the complete address and e-mail.
- Do not use any logos (company, institute, ...) on the abstracts.
- Please no formatting, flat text only..
- Figures most be supplied as separate *.jpg images.
- Do not use halftoning or colour: We publish in pure black and white.
- Include your e-mail address.
Posters: The same rules apply for the abstracts to be submitted. Poster size should not exceed 146 H x 118 W cm (size of pin wall). There will be a defined poster session.
SGMS School: For details see the SGMS website. Register via the SGMS meeting registration form
Please send your registration to registration(at)sgms(dot)ch not later than October 1st, 2019. There is no need to register personally at the Dorint Hotel Blüemlisalp, Beatenberg! The SGMS committee will manage all hotel reservations and payments. We will strictly follow a first come first serve policy for the hotel room assignment.
SGMS School Registration on the same registration form. Please tick the correct box if you are attending the School, Meeting or Both
There will be an additional fee of CHF 50.- for late registration (after October 1st, 2019).
All PhD students attending the annual SGMS meeting pay a reduced fee of CHF 100.-, but will have to share rooms.
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will be availabe mid September
Department of Chemistry and Biochemistry
NIH Resouce for Mass Spectrometry Guided Structural Biology
The Ohio State University
United States of America
Characterization of the overall topology and inter-subunit contacts of protein complexes, and their assembly/disassembly and unfolding pathways, is critical because protein complexes regulate key biological processes, including processes important in understanding and controlling disease. Tools to address structural biology problems continue to improve. Native mass spectrometry and associated technologies are becoming an increasingly important component of the structural biology toolbox. When the mass spectrometry approach is used early or mid-course in a structural characterization project, it can provide answers quickly using small sample amounts and samples that are not fully purified. Integration of sample preparation/purification with effective dissociation methods, ion mobility, and computational approaches provide a MS workflow that can be enabling in biochemical, synthetic biology, and systems biology approaches. Beyond what MS can provide as a stand-alone tool, MS can also guide and/or be integrated with other structural biology approaches such as NMR, X-ray crystallography, and cryoEM. MS can determine whether the complex of interest exists in a single or in multiple oligomeric states and can provide characterization of topology/intersubunit connectivity, and other structural features. Examples will be presented to illustrate the role MS and surface-induced dissociation can play in guiding a structural biology workflow and will include designed protein complexes and isolated or recombinant protein and nucleoprotein complexes. [ top ]
Dietrich A. Volmer
Department of Chmistry
Humboldt Universität zu Berlin
Lignin's aromatic building blocks provide a chemical resource that is, in theory, ideal for substitution of aromatic petrochemicals. Moreover, degradation of lignin has the potential to generate many high-value chemicals for technical applications. To fully assess the molecular value of lignin wastes, chemical characterization methods are required that are able to resolve the highly complex mixtures of thousands of components. Due to lignin’s inherent intricate structural motifs and additional heteroatoms being introduced during chemical degradation procedures and due to the highly variable relative abundances within the material, different analytical techniques often give different estimates of the lignin product composition, even for the same sample. Among the different modern instrumental techniques, high-resolution mass spectrometry (HRMS) is currently the most suitable technique for lignin analysis. This presentation summarizes different mass spectrometry and data-processing methods developed in our laboratory for application to full-scan raw data from high-resolution mass spectrometry experiments of decomposed lignin samples. Data from different ionization techniques such as ESI, APCI, APPI and MALDI are compared as well as rapid characterizations by different ambient ionization techniques. The discussed graphical and statistical methods provide initial classification of the major lignin components and elucidation of the main structural features without the need for time-consuming tandem mass spectrometry analyses. [ top ]
Department of Chemistry and Pharmacy
Contemporary products are composed of a multitude of chemical constituents providing functionalities such as colour, texture, haptic sensations or flexibility, to name but a few. Commodities and products travel the world in a globalized market and add to an ever-growing complexity in our chemical world.
While certain materials are commonly (accepted to be) associated with characteristic smells, others increasingly elicit odours that would not typically be expected to appear – most recently in a range of articles of daily use, including children’s products and sports gear.
Our research group has been increasingly active in recent years in compiling data on such unforeseen smells and establishing their chemical underpinnings. Studies have targeted glues and adhesives, paints, children’s products, and recycled regrinds, to name but a few. Sniffing out the causative substances has much in common with detective work, as potent odorants are commonly not straightforward to detect analytically. Accordingly, one needs either skilled assessors that at the same time are talented chemical analysts or intelligent machines – ideally both. Facing these challenges in a modern world of chemistry, the team of the Department of Sensory Analytics at Fraunhofer IVV has joined forces with the Campus of the Senses initiative (www. campus-der-sinne.fraunhofer.de) with an aim to develop novel strategies to unveil what is often not visible to the eyelet alone sniffable by a machine.
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Institut Européen de Chimie et Biologie
University of Bordeaux
Valérie Gabelica studied Chemistry and obtained her PhD in Sciences in 2002 at the University of Liège. After a postdoc in Frankfurt as Humboldt fellow, she rejoined the Mass Spectrometry Laboratory in Liège where she obtained an FNRS research associate position in October 2005. She joined the IECB in 2013 with the support of an Atip-Avenir grant, and became an Inserm research director (DR2) in December 2013. She obtained an ERC Consolidator grant in 2014. Her main research interests are fundamental aspects of mass spectrometry and its application to non-covalent complexes in general and nucleic acid complexes in particular, with research themes spanning from physical chemistry to biophysics and structural chemistry and biology.
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